Кафедра біології

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https://ekmair.ukma.edu.ua/handle/123456789/12295

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Browsing Кафедра біології by Author "Kozakevych, Roman"

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    Antibacterial properties of composite materials based on metal/metal-oxide nanoparticles, nanosilica and polylactid acid
    (2025) Bespalko, Oleksandr; Vakuliuk, Polina; Furtat, Iryna; Pryshchepa, Oleksandra; Kozakevych, Roman; Pomastowskі, Paweł
    The global rise in antimicrobial resistance necessitates the development of alternative materials with effective antibacterial properties. This study compares two classes of nanocomposites: silver nanoparticle (AgNP)- and zinc oxide (ZnO)-based systems, both immobilized on silica (SiO₂) and treated with polylactic acid (PLA) to enhance biocompatibility and biodegradability. AgNP-containing composites (SiO₂- Ag and SiO₂-Ag-PLA) exhibited potent, broad-spectrum antibacterial activity, particularly against Gram-negative E. coli and K. pneumoniae, though activity decreased when modified with PLA—likely due to reduced ion release and surface coverage interference.
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    Antibacterial properties of silver-containing composite materials based on silica and polylactic acid
    (2025) Bespalko, Oleksandr; Vakuliuk, Polina; Furtat, Iryna; Pryshchepa, Oleksandra; Kozakevych, Roman; Pomastowskі, Paweł
    This study aimed to investigate composite materials containing silver nanoparticles (AgNPs) impregnated on silica (SiO2) and incorporated into a polylactic acid (PLA) matrix.
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    Antibacterial properties of zinc oxide-containing composite materials based on silica and polylactic acid
    (ЛНУ імені Івана Франка, 2025) Bespalko, Oleksandr; Vakuliuk, Polina; Furtat, Iryna; Pryshchepa, Oleksandra; Kozakevych, Roman; Pomastowski, Paweł
    Antimicrobial resistance poses a critical threat to global health, as conventional drugs increasingly fail against multidrug-resistant pathogens. A key challenge lies in the inability of many antimicrobials to penetrate microbial membranes or act effectively against intracellular infections. Nanoparticles (NPs) offer a promising alternative due to their unique physicochemical properties and broad-spectrum antimicrobial activity. Among these, zinc oxide nanoparticles (ZnO NPs) are especially notable for their low cytotoxicity and effectiveness against resistant strains.
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    Physicochemical and antibacterial properties of ornidazole based nanocomposites for medical application
    (2025) Avramenko, Viktoriia; Vakuliuk, Polina; Furtat, Iryna; Pryshchepa, Oleksandra; Kozakevych, Roman; Demianenko, Eugeniy; Murlanova, Tetiana; Smarsly, Bernd; Pomastowskі, Paweł
    This study analyzed nanocomposites with ornidazole – an antimicrobial agent effective against anaerobic bacteria and protozoa.