Кафедра біології
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Browsing Кафедра біології by Subject "Ag-based composites"
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Item Antibacterial properties of composite materials based on metal/metal-oxide nanoparticles, nanosilica and polylactid acid(2025) Bespalko, Oleksandr; Vakuliuk, Polina; Furtat, Iryna; Pryshchepa, Oleksandra; Kozakevych, Roman; Pomastowskі, PawełThe global rise in antimicrobial resistance necessitates the development of alternative materials with effective antibacterial properties. This study compares two classes of nanocomposites: silver nanoparticle (AgNP)- and zinc oxide (ZnO)-based systems, both immobilized on silica (SiO₂) and treated with polylactic acid (PLA) to enhance biocompatibility and biodegradability. AgNP-containing composites (SiO₂- Ag and SiO₂-Ag-PLA) exhibited potent, broad-spectrum antibacterial activity, particularly against Gram-negative E. coli and K. pneumoniae, though activity decreased when modified with PLA—likely due to reduced ion release and surface coverage interference.